赵春深简介
赵春深，男，1978年2月，沈阳药科大学博士学位。贵州大学教授，贵州大学药学院制药工程药研室主任，硕士研究生导师，主要从事医药中间体及新药研发工作。
邮箱：390214939@qq.com
1996年9月1日-2000年7月1日 沈阳药科大学 学士学位
2000年9月1日-2003年7月1日 沈阳药科大学 硕士学位
2003年9月1日-2006年7月1日 沈阳药科大学 博士学位
2007年4月1日-2008年3月31日 日本京都药科大学 博士后
2006年9月-2018年12月 贵州大学 副教授
2013年 被贵阳市科技局聘为“贵州市科技特派员”
2015年 被贵州省科技厅聘为“贵州省科技特派员”
2018年12月-至今 贵州大学 教授
【主持项目】
1. 系列医药中间体的开发 横向主持2018.01-2021.01
2. 吡啶类合成砌块的研发 贵州省科技厅基金 主持 2013-05 至2015-06
3. 基于吡啶并咪唑联氨传感材料合成及性能研究贵州省科技厅参与．2015-01 至2017-12
4. 蛋白酪氨酸激酶抑制剂的合成研究，产学研项目 2012-09-01至 2017-09-31
5. 阿比朵尔衍生物的合成研究，产学研项目 主持 2012-09-01至 2017-09-31
【近期发表论文】
1. Hong Sun, Liyuan Deng, Weiyin Hu, Tianhui Liao, Weike Liao, Huifang Chai, Chunshen Zhao*. Synthesis, crystal structure, vibrational properties and DFT studies of 4-(furan-2-ylmethyl)-1-(thiomorpholinomethyl)-[1,2,4]triazolo[4,3-a]quinazon-5(4H)-one.Journal of Molecular Structure. 2022, DOI: 10.1016/j.molstruc.2021.131395.
2. Weiyin Hu, Liyuan Deng, Hong Sun, Zhixu Zhou, Huifang Chai*, Chunshen Zhao*. Synthesis, crystal structure and DFT study of a new compound 4-(2-chlorobenzyl)-1-(5-fluoro-2-hydroxy-3-(thiomorpholinomethyl)phenyl-[1,2,4] triazolo[4,3-a]quinazolin-5(4H)-one. Journal of Heterocyclic Chemistry, 2021, DIO: 10.1002/jhet.4333.
3. Peng-Yue Huang, Zhi-Song Yang, Qing-Mei Wu, De-Zheng Yang, Jun-Jiang Chen, Hui-Fang Chai, Chun-Shen Zhao. Synthesis, crystal structure and DFT study of compound methyl 3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate and (2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)(pyrrolidin-1-yl)methanone.Journal of Structural Chemistry, 2021, 62(6): 845-852.
4. Zhi-Song Yang, Peng-Yue Huang, Jun-Jiang Chen, Yu-Mei Chen, Ting Gao, Hui-Fang Chai, Chun-Shen Zhao*. Synthesis, crystal structure and DFT study of 1-(2-bromobenzyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole. Journal of Structural Chemistry, 2021, 62(6): 928-937.
5. Ye Liu, Hao Deng, Qian Ren, Zhixu Zhou, Chunshen Zhao*, Huifang Chai*. Synthesi, characterization of a new compound 4-(2-chlorobenzyl)imidazo[1,2-a]quinazolin-5 (4H)-one and DFT study of crystal structure, MEP and HOMO–LUMO. Journal of Structural Chemistry, 2021, 62(8): 1372-1379.
6. Qian Ren, Peng-Yue Huang Ye Liu, Wei-Ke Liao, Zhi-Xu Zhou*, Chun-Shen Zhao*. Synthesis, crystal structure and DFT study of a novel compound 4-(2-chlorobenzyl)-1- (5-nitro-2-(pyrrolidin-1-yl)phenyl)-[1,2,4]triazolo[4,3-a]quinazolin-5(4H)-one. Journal of Structural Chemistry, 2021, 62(9): 1571-1581.
7. Minggang Teng, Zhixu Zhou, Yumei Qin, Yongli Zhao, Chunshen Zhao*, Jianxin Cao*. A water-soluble fluorescence sensor with high specificity for detecting hydrazine in river water detection and A549 cell imaging. Sensors & Actuators: B. Chemical, 2020, 311: 127914.
8. Qiuyan Zhang, Zhuyan Huang, Yi Le, Xue Zou, Zhixu Zhou, Chunshen Zhao*. Synthesis, crystal structure and DFT study of 6-hydroxybentazon. Chinese Journal of Structural Chemistry. 2020, 39(2): 269-278.
9. Ye Liu, Yongli Zhao, Qian Ren, Zhixu Zhou, Huifang Chai, Chunshen Zhao*. Synthesis, crystal structure and DFT study of a novel planar bipyridyl compound 6,6’-bis(trifluoromethyl)-3,3’-bipyridine. Journal of Molecular Structure. 2020, 1208: 127869.
10. Zhang Dan; Han Jie; Lu Wenchao; Lian Fulin; Wang Jun; Lu Tian; Tao Hongru; Xiao Senhao; Zhang Fengcai; Liu Yu-Chih; Liu Rongfeng; Zhang Naixia; Jiang Hualiang; Chen Kaixian; Zhao Chunshen*; Luo Cheng*. Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening. Bioorganic Chemistry, 2019, 86: 494-500.
11. Peng Zhao, Zhu-yan Huang, Chunshen Zhao*, Sheng Liu*. Facile Formation of Eight-membered Rings of Indoloazocine Framework via Intramolecular Oxidative Heck Cyclization. J. Heterocyclic Chem., 2019, 56, 108-113.
12. Yumei Qin, Dan Long Xiong Zhu, Zhixu Zhou, Huifang Chai*, Chunshen Zhao*. Synthesis, crystal structure and DFT study of a new compound 6-(2-fluorophenyl)-N-(p-tolyl)imidazo[1,2-a]pyridine-2-carboxamide, Journal of Structural Chemistry, 2019, 60(12):1917-1924.
13. Chunshen Zhao*, Fei Li, Shuo Yang, Li Liu, Zhuyan Huang, Huifang Chai*. Chemoselective iodination of 6-substituted imidazo[1,2-a]pyridine. Chemistry of Heterocyclic Compounds, 2018, 54(5): 568–571.
