李先涛 教授
常用邮箱:li76915@163.com
联系地址:贵州大学医学院(南校区)309室
简介:
学术背景:男,博士,教授,博士生导师,在国内外名校学习工作多年,具有扎实的医学研究背景。
研究方向:心脑血管疾病及药物作用机制
拟开展课题:
1:抗痴呆药物神经保护作用的离子通道机制
2:抗心律失常药物多靶点研究
代表性成果:
代表性论文(标*为通讯作者):
(1) Qiu XY, Li XT*. Estrogen-induced downregulation of TASK-1 expression through estrogen receptor β in N2A cells. Mol Biol Rep, 2022;49(1):817-819. (SCI)
(2) Li XT*. Alzheimer’s disease therapy based on Acetylcholinesterase inhibitor/blocker effects on voltage-gated potassium channels. Metab Brain Dis. 2022;37(3):581-587. (SCI)
(3) Li K, Li XT*. Beneficial effects of carvedilol modulating potassium channels on the control of glucose. Biomed Pharmacother. 2022, 150:113057. (SCI)
(4) Hu XM, Reng S, Li K, Li XT*. Tacrine modulates Kv2.1 channel gene expression and cell proliferation. Int J Neurosci, 2020, 130(8):781-787. (SCI)
(5) Cheng N, Reng S, Yang JF, Liu XM, Li XT*. Carvedilol blockage of delayed rectifier Kv2.1 channels and its molecular basis. Eur J Pharmacol. 2019; 855:50-55. (SCI)
(6) Yang JF, Cheng N, Reng S, Liu XM, Li XT*. Characterization and molecular basis for the block of Kv1.3 channels induced by carvedilol in HEK293 cells. Eur J Pharmacol. 2018; 834: 206-212. (SCI)
科研项目:近五年主持国家部委和横向项目多项。